研究業績Achievement

研究業績

2022年~

  1. #Ozawa M, Mori H, Endo T, Yamauchi-Ishikawa Y, Motooka D, Emori C, #Ikawa M.
    Age-related decline in spermatogenic activity accompanied by endothelial cell senescence in male mice.
    iScience. 2023 Nov 13;26(12):108456. doi: 10.1016/j.isci.2023.108456. eCollection 2023 Dec 15.
    https://pubmed.ncbi.nlm.nih.gov/38077127/
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  2. #Kiyozumi D, Shimada K, Chalick M, Emori C, Kodani M, Oura S, Noda T, Endo T,  Matzuk MM,  #Wreschner DH, #Ikawa M.
    A small secreted protein NICOL regulates lumicrine-mediated sperm maturation and male fertility
    Nat Commun. 2023 Apr 24;14(1):2354. doi: 10.1038/s41467-023-37984-x.
    https://pubmed.ncbi.nlm.nih.gov/37095084/
     
  3. Morohoshi A, #Miyata H, Tokuhiro K, Iida-Norita R, Noda T, Fujihara Y & #Ikawa M.
    Testis-enriched ferlin, FER1L5, is required for Ca2+-activated acrosome reaction and male fertility
    Sci Adv. 2023 Jan 25;9(4):eade7607. doi: 10.1126/sciadv.ade7607. Epub 2023 Jan 25.
    https://pubmed.ncbi.nlm.nih.gov/36696506/
     
  4. Oura S, Ninomiya A, Sugihara F, Matzuk MM & #Ikawa M.
    Proximity-dependent biotin labeling in testicular germ cells identified TESMIN-associated proteins.
    Sci Rep. 2022 Dec 23;12(1):22198. doi: 10.1038/s41598-022-26501-7.
    https://pubmed.ncbi.nlm.nih.gov/36564444/
     
  5. #Ozawa M, Taguchi J, Katsuma K, Ishikawa-Yamauchi Y, Kikuchi M, Sakamoto R, Yamada Y & #Ikawa M.
    Efficient simultaneous double DNA knock-in in murine embryonic stem cells by CRISPR/Cas9 ribonucleoprotein-mediated circular plasmid targeting for generating gene-manipulated mice.
    Sci Rep. 2022 Dec 13;12(1):21558. doi: 10.1038/s41598-022-26107-z.
    https://pubmed.ncbi.nlm.nih.gov/36513736/
  6. Oura S, Mori H, #Ikawa M.
    Genome editing in mice and its application to the study of spermatogenesis.
    Gene and Genome Editing. 2022
    https://www.sciencedirect.com/science/article/pii/S2666388022000041
     
  7. *#Ozawa M, *Emori C, #Ikawa M.
    CRISPR/Cas9-Mediated Highly Efficient Gene Targeting in Embryonic Stem Cells for Developing Gene-Manipulated Mouse Models.
    J. Vis. Exp. 2022 (186), e64385, doi:10.3791/64385.
    https://www.jove.com/t/64385/crisprcas9-mediated-highly-efficient-gene-targeting-embryonic-stem
     
  8. Hirano K, Naomi Y, Nakamura Y, Sato T, Sato T, Ishiguro K, Ogawa T & #Yoshida S.
    Temperature sensitivity of DNA double-strand break repair underpins heat-induced meiotic failure in mouse spermatogenesis
    Commun Biol. 2022 May 26;5(1):504. doi: 10.1038/s42003-022-03449-y.
    https://www.jove.com/t/64385/crisprcas9-mediated-highly-efficient-gene-targeting-embryonic-stem