研究業績Achievement

研究業績

2022年～

  1. Ito Y,Kawauchi I,Yanagita Y,Sakai Y,Nishikawa M,Arakawa H,Kadoguchi M,Tamai I,Esashika K,Takahashi J,Ando O,Satoh T,Imai I,Adachi S,Chiba D,Arai K,Shiota K,Sawaguchi T,Yoshioka T,Fujimoto T, Yoshikuni T, Mizuno A, Aihara T, Sakura T,Kimura H&#Nakae H
    Microphysiological systems for realizing microenvironment that mimics human physiology—functional material and its standardization applied to microfluidics
    SPRINGER NATURE. 2024/08/09 https://doi.org/10.1007/s42247-024-00822-x
    https://link.springer.com/article/10.1007/s42247-024-00822-x

  2. #Tokuoka Y, #Endo T, #Morikura T, #Hiradate Y, #Ikawa M,  #Funahashi A
    Deep learning–based automated prediction of mouse seminiferous tubule stage by using bright-field microscopy
    biorxiv. 2024.08.07.doi: https://doi.org/10.1101/2024.08.07.606973
    https://www.biorxiv.org/content/10.1101/2024.08.07.606973v1

  3. Hashimoto K, Arakawa H,  Imamura R,  Nishimura T, Kitajima S, Sato T, Makiyama K,  #Ogawa T, #Yokota S,
    A novel alternative method for long-term evaluation of male reproductive toxicity and its recovery using a pre-pubertal mouse testis organ culture system
    J Appl Toxicol . 2024 May;44(5):784-793. doi: 10.1002/jat.4584. Epub 2024 Jan 23.
    https://pubmed.ncbi.nlm.nih.gov/38262615/

  4. #Ozawa M, Mori H, Endo T, Yamauchi-Ishikawa Y, Motooka D, Emori C, #Ikawa M.
    Age-related decline in spermatogenic activity accompanied by endothelial cell senescence in male mice.
    iScience. 2023 Nov 13;26(12):108456. doi: 10.1016/j.isci.2023.108456. eCollection 2023 Dec 15.
    https://pubmed.ncbi.nlm.nih.gov/38077127/
     
  5. Hashimoto K, Odaka H,Ishikawa-Yamauchi  Y, Nagata S,Nakamura H,Kimura H, Sato T, Makiyama K, #Ogawa T​.
    Culture-space control is effective in promoting haploid cell formation and spermiogenesis in vitro in neonatal mice.
    Sci Rep. 2023 Jul 31;13(1):12354. doi: 10.1038/s41598-023-39323-y.
    https://pubmed.ncbi.nlm.nih.gov/37524742/
     
  6. Matsumura T, Katagiri K, Yao T, Ishikawa-Yamauchi Y,Nagata S, Hashimoto K,Sato T, Kimura H, Shinohara T, Sanbo M, #Hirabayashi M, #Ogawa T,
    Generation of rat offspring using spermatids produced through in vitro spermatogenesis
    Sci Rep. 2023 Jul 26;13(1):12105. doi: 10.1038/s41598-023-39304-1.
    https://pubmed.ncbi.nlm.nih.gov/37495678/
     
  7. #Kiyozumi D, Shimada K, Chalick M, Emori C, Kodani M, Oura S, Noda T, Endo T,  Matzuk MM,  #Wreschner DH, #Ikawa M.
    A small secreted protein NICOL regulates lumicrine-mediated sperm maturation and male fertility
    Nat Commun. 2023 Apr 24;14(1):2354. doi: 10.1038/s41467-023-37984-x.
    https://pubmed.ncbi.nlm.nih.gov/37095084/
     
  8. Feng X, Matsumura T, Yamashita Y, Sato T, Hashimoto K, Odaka H, Makino Y, Okada Y, Nakamura H, Kimura H, Fujii T ,#Ogawa T.
    In vitro spermatogenesis in isolated seminiferous tubules of immature mice
    PLoS One. 2023 Apr 6;18(4):e0283773. doi: 10.1371/journal.pone.0283773. eCollection 2023.
    https://pubmed.ncbi.nlm.nih.gov/37023052/
     
  9. Morohoshi A, #Miyata H, Tokuhiro K, Iida-Norita R, Noda T, Fujihara Y & #Ikawa M.
    Testis-enriched ferlin, FER1L5, is required for Ca2+-activated acrosome reaction and male fertility
    Sci Adv. 2023 Jan 25;9(4):eade7607. doi: 10.1126/sciadv.ade7607. Epub 2023 Jan 25.
    https://pubmed.ncbi.nlm.nih.gov/36696506/
     
  10. Oura S, Ninomiya A, Sugihara F, Matzuk MM & #Ikawa M.
    Proximity-dependent biotin labeling in testicular germ cells identified TESMIN-associated proteins.
    Sci Rep. 2022 Dec 23;12(1):22198. doi: 10.1038/s41598-022-26501-7.
    https://pubmed.ncbi.nlm.nih.gov/36564444/
     
  11. #Ozawa M, Taguchi J, Katsuma K, Ishikawa-Yamauchi Y, Kikuchi M, Sakamoto R, Yamada Y & #Ikawa M.
    Efficient simultaneous double DNA knock-in in murine embryonic stem cells by CRISPR/Cas9 ribonucleoprotein-mediated circular plasmid targeting for generating gene-manipulated mice.
    Sci Rep. 2022 Dec 13;12(1):21558. doi: 10.1038/s41598-022-26107-z.
    https://pubmed.ncbi.nlm.nih.gov/36513736/
     
  12. Oura S, Mori H, #Ikawa M.
    Genome editing in mice and its application to the study of spermatogenesis.
    Gene and Genome Editing. 2022
    https://www.sciencedirect.com/science/article/pii/S2666388022000041
     
  13. #Ozawa M, *Emori C, #Ikawa M.
    CRISPR/Cas9-Mediated Highly Efficient Gene Targeting in Embryonic Stem Cells for Developing Gene-Manipulated Mouse Models.
    J. Vis. Exp. 2022 (186), e64385, doi:10.3791/64385.
    https://www.jove.com/t/64385/crisprcas9-mediated-highly-efficient-gene-targeting-embryonic-stem
     
  14. Hirano K, Naomi Y, Nakamura Y, Sato T, Sato T, Ishiguro K, Ogawa T & #Yoshida S.
    Temperature sensitivity of DNA double-strand break repair underpins heat-induced meiotic failure in mouse spermatogenesis
    Commun Biol. 2022 May 26;5(1):504. doi: 10.1038/s42003-022-03449-y.
    https://www.jove.com/t/64385/crisprcas9-mediated-highly-efficient-gene-targeting-embryonic-stem
     
  15. #Kiyozumi D, #Ikawa M.
    Proteolysis in Reproduction: Lessons From Gene-Modified Organism Studies
    Front Endocrinol (Lausanne). 2022 May 4:13:876370. doi: 10.3389/fendo.2022.876370. eCollection 2022.
    https://pubmed.ncbi.nlm.nih.gov/35600599/