ASPIRE R5年度-9年度先端国際共同研究推進プログラム 次世代生殖補助医療に資する国際共同研究 International Collaborative Research Pioneering Next-Generation Assisted Reproductive Medicine

研究業績Achievements

2024

  1. Inhibition of ROS1 activity with lorlatinib reversibly suppresses fertility in male mice.
    Oyama Y, Shimada K, #Miyata H, Iida-Norita R, Emori C, Kamoshita M, Oura S, Katayama R, Matzuk MM, #Ikawa M.
    Andrology. 2024 Nov 20. doi: 10.1111/andr.13808. Online ahead of print.
    https://pubmed.ncbi.nlm.nih.gov/39568175/
     
  2. Loss of CCDC188 causes male infertility with defects in the sperm head-neck connection in mice
    Qiu Y, #Shimada K , Yamamoto K , #Ikawa M
    Biol Reprod. 2024 Sep 18:ioae137. doi: 10.1093/biolre/ioae137. Online ahead of print.
    https://pubmed.ncbi.nlm.nih.gov/39292630/
     
  3. Sendai virus-mediated RNA delivery restores fertility to congenital and chemotherapy-induced infertile female mice
    Kanatsu-Shinohara M, Morimoto H, Liu T, Tamura M, #Shinohara T
    PNAS Nexus. 2024 Sep 3;3(9):pgae375. doi: 10.1093/pnasnexus/pgae375. eCollection 2024 Sep.
    https://pubmed.ncbi.nlm.nih.gov/39262851/
     
  4. Lower developmental potential of rat zygotes produced by ooplasmic injection of testicular spermatozoa versus cauda epididymal spermatozoa
    Ide M, Saito I, Sanbo M, Kanatsu-Shinohara M, Shinohara T, #Hirabayashi M, #Hochi S​​​​​
    J Reprod Dev. 2024 Aug 7;70(4):254-258. doi: 10.1262/jrd.2024-030. Epub 2024 May 11.
    https://pubmed.ncbi.nlm.nih.gov/38735740/
     
  5. Spermatogonial stem cells in the 129 inbred strain exhibit unique requirements for self-renewal
    Kanatsu-Shinohara M, Yamamoto T, Morimoto H, Liu T, #Shinohara T ​​​​​
    Development. 2024 Jun 15;151(12):dev202553. doi: 10.1242/dev.202553. Epub 2024 Jun 27.
    https://pubmed.ncbi.nlm.nih.gov/38934417/
    ​​​​​​​
  6. Individual disruption of 12 testis-enriched genes via the CRISPR/Cas9 system does not affect the fertility of male mice
    Suzuki A, #Yabuta N ​​​​​​, Shimada K, Mashiko D, Tokuhiro K, Oyama Y, Miyata H, Garcia TX, Matzuk MM, ​​​#Ikawa M
    J Reprod Immunol. 2024 Apr 29:163:104252. doi: 10.1016/j.jri.2024.104252. Online ahead of print.
    https://pubmed.ncbi.nlm.nih.gov/38697008/
     

後日掲載予定

招待

Date Kind Presenters Conference Title
3/30 招待講演 Masahito Ikawa ASA & ICA 2025 Testis-enriched genes and their functions​ during spermatogenesis and fertilization​
3/29 招待講演 Keisuke Shimada and Masahito Ikawa ASA & ICA 2025 Molecular Mechanism Analysis Involved in Mitochondrial Sheath Formation
7/19 招待講演 伊川 正人 SSR 57th Annual Meeting Testis-enriched genes and their functions during spermatogenesis and fertilization

6/4

 研究発表 伊川 正人 AMED/ASPIRE International Collaborative Research Pioneering Next-Generation Assisted Reproductive Medicine


応募

Date Kind Presenters Conference Title
5/2 Poster

Daisuke Mashiko, Takashi Morikura, Shingo Tonai, Yuta Tokuoka, Tsutomu Endo, Akira Funahashi, Masahito Ikawa

 2024 North American Testis Workshop Agenda Development of an AI-based auto mouse seminiferous tubule staging system using slide scanner
4/29 Poster Maki Kamoshita, Hiroki Shirai, Hiroko Nakamura, Takehiko Ogawa, Hiroshi Kimura, Masahito Ikawa  ASA 2024 Annual Meeting Development of a membrane ceiling device for in vitro spermatogene

後日掲載予定

後日掲載予定

  1. がんの男児の精巣保存、成人後の不妊治療に備え
    伊川　正人、林　克彦
    読売新聞　2024.06.24