I begun the OOSP project in 2015 when I arrived to EGR. My goal was to find genes important for female fertility, and the OOSP family seemed to be the best candidate for that. We started from knocking out each gene individually and then as technology advanced, we were able to make a triple knockout female mouse! Unfortunately, my time at EGR ended just as the TKO mouse was created because I decided to return back to the US to pursue medical school. Thanks to my co-author Mayo and everyone else who supported us during these past few years, we were able to publish the one gene family that was so close to my heart. Honestly, with the publication of this paper, it feels like this chapter in my life has officially closed. Thank you to everyone who has helped me grow. And hopefully, when I return back to Japan, I will be Ferheen Abbasi, MD.
CRISPR/Cas9-Mediated Genome Editing Reveals Oosp Family Genes Are Dispensable for Female Fertility in Mice.