#Miyata H, Shimada K, Kaneda Y, #Ikawa M
Development of functional spermatozoa in mammalian spermiogenesis Development. 2024 Jul 15;151(14):dev202838. doi: 10.1242/dev.202838. Epub 2024 Jul 22. https://pubmed.ncbi.nlm.nih.gov/39036999/
#Kiyozumi D, Ikawa M.
ADGRG2 is dispensable for lumicrine signalling regulating epididymal initial segment differentiation and gene expression.
Biology of Reproduction. ioad087. Published online 02 August 2023. doi: 10.1093/biolre/ioad087/7235675 https://pubmed.ncbi.nlm.nih.gov/37531264/
#Lu Y, #Ikawa M.
Eukaryotic fertilization and gamete fusion at a glance.
J Cell Sci. 2022 Nov 15;135(22):jcs260296. doi: 10.1242/jcs.260296. Epub 2022 Nov 23. https://pubmed.ncbi.nlm.nih.gov/36416181/
Kiyozumi D, Ikawa M.
Proteolysis in Reproduction: Lessons From Gene-Modified Organism Studies.
Front. Endocrinol., 04 May 2022 | https://doi.org/10.3389/fendo.2022.876370 https://pubmed.ncbi.nlm.nih.gov/35600599/
#Miyagawa S, Maeda A, Toyama C, Kogata S, Okamatsu C, Yamamoto R, Masahata K, Kamiyama M, Eguchi H, Watanabe M, Nagashima H, Ikawa M, Matsunami K, Okuyama H.
Aspects of the Complement System in New Era of Xenotransplantation.
Front Immunol. 2022 Apr 14:13:860165. doi: 10.3389/fimmu.2022.860165. eCollection 2022. https://pubmed.ncbi.nlm.nih.gov/35493484/
Miyata H, Morohoshi A,Ikawa M.
Analysis of the Sperm Flagellar Axoneme Using Gene-Modified Mice.
Exp Anim. 2020 Nov 12;69(4):374-381. doi: 10.1538/expanim.20-0064. Epub 2020 Jun 18. https://pubmed.ncbi.nlm.nih.gov/32554934/
Fujihara Y, Miyata H, Ikawa M.
Factors controlling sperm migration through the oviduct revealed by gene-modified mouse models. Exp Anim. 2018 Jan 22. doi: 10.1538/expanim.17-0153. https://www.ncbi.nlm.nih.gov/pubmed/29353867
Abbasi F, Miyata H, Ikawa M.
Revolutionizing male fertility factor research in mice by using the genome editing tool CRISPR/Cas9. Reproductive Medicine and Biology. 2017 Oct 14. doi: 10.1002/rmb2.12067. https://www.ncbi.nlm.nih.gov/pubmed/29371815
Tobita T, Kiyozumi D, Ikawa M.
Placenta-specific gene manipulation using lentiviral vector and its application. Placenta. 2017 Sep 28. pii: S0143-4004(17)31126-8. https://www.ncbi.nlm.nih.gov/pubmed/28988726
Noda T, Oji A, Ikawa M.
Genome Editing in Mouse Zygotes and Embryonic Stem Cells by Introducing SgRNA/Cas9 Expressing Plasmids. Methods Mol Biol. 2017 1630:67-80. https://www.ncbi.nlm.nih.gov/pubmed/28643250
Young SA, Aitken RJ, Ikawa M.
Advantages of using the CRISPR/Cas9 system of genome editing to investigate male reproductive mechanisms using mouse models. Asian J Androl. 2015 Jul-Aug;17(4):623-7. http://www.ncbi.nlm.nih.gov/pubmed/25994645
Inoue N, Ikawa M, Okabe M.
The mechanism of sperm-egg interaction and the involvement of IZUMO1 in fusion. Asian J Androl. 2011; 13(1):81-7. http://www.ncbi.nlm.nih.gov/pubmed/21057513
Ikawa M, Inoue N, Benham AM, Okabe M.
Fertilization: a sperm's journey to and interaction with the oocyte. J Clin Invest 2010;120(4):984-94. http://www.ncbi.nlm.nih.gov/pubmed/20364096
Ikawa M, Inoue N, Okabe M.
Mechanisms of sperm-egg interactions emerging from gene-manipulated animals. Int J Dev Biol 2008;52(5-6):657-64. http://www.ncbi.nlm.nih.gov/pubmed/18649279
Sato T, Kurokawa M, Nakashima Y, Ida T, Takahashi T, Fukue Y, Ikawa M, Okabe M, Kangawa K, Kojima M.
Ghrelin deficiency does not influence feeding performance. Regul Pept 2008;145(1-3):7-11. http://www.ncbi.nlm.nih.gov/pubmed/17913260
Inoue N, Yamaguchi R, Ikawa M, Okabe M.
Sperm-egg interaction and gene manipulated animals. Soc Reprod Fertil Suppl 2007;65:363-371. http://www.ncbi.nlm.nih.gov/pubmed/17644977
Ikawa M, Yamada S, Nakanishi T, Okabe M.
Green fluorescent protein (GFP) as a vital marker in mammals. Curr Top Dev Biol 1999;44:1-20. http://www.ncbi.nlm.nih.gov/pubmed/9891875
Imai E, Akagi Y, Isaka Y, Ikawa M, Takenaka M, Hori M, Okabe M.
Glowing podocytes in living mouse: transgenic mouse carrying a podocyte-specific promoter. Exp Nephrol. 1999;7(1):63-6. http://www.ncbi.nlm.nih.gov/pubmed/9892816?dopt=Abstract
Ikawa M, Yamada S, Nakanishi T, Okabe M.
'Green mice' and their potential usage in biological research. FEBS Lett 1998; 430(1-2):83-87. http://www.ncbi.nlm.nih.gov/pubmed/9678599
Akagi Y, Isaka Y, Akagi A, Ikawa M, Takenaka M, Moriyama T, Yamauchi A, Horio M, Ueda N, Okabe M, Imai E.
Transcriptional activation of a hybrid promoter composed of cytomegalovirus enhancer and beta-actin/beta-globin gene in glomerular epithelial cells in vivo. Kidney Int. 1997; 51(4):1265-9. http://www.ncbi.nlm.nih.gov/pubmed/9083295
宮田治彦,伊川正人. マウスの生殖能力に必須な精子カルシニューリンは男性避妊薬の標的となりうる
Japanese Scientists in Science 2015
American Association for the Advancement of Science(AAAS) 2016;64 Japanese_Scientists_Science 2015.pdf