Oura S, Hino T, Satoh T, Noda T, Koyano T, Isotani A, Matsuyama M, Akira S, Ishiguro KI, #Ikawa M.
Trim41 is required to regulate chromosome axis protein dynamics and meiosis in male mice. PLoS Genet. 2022 Jun 1;18(6):e1010241. doi: 10.1371/journal.pgen.1010241. Online ahead of print. https://pubmed.ncbi.nlm.nih.gov/35648791/
Kaneda Y, #Miyata H, Shimada K, Oyama Y, Iida-Norita R, #Ikawa M.
IRGC1, a testis-enriched immunity related GTPase, is important for fibrous sheath integrity and sperm motility in mice. Dev Biol. 2022 May 23:S0012-1606(22)00099-9. doi: 10.1016/j.ydbio.2022.05.011. Online ahead of print. https://pubmed.ncbi.nlm.nih.gov/35618043/
Oyama Y, #Miyata H, Shimada K, Larasati T, Fujihara Y, #Ikawa M
TULP2 deletion mice exhibit abnormal outer dense fiber structure and male infertility. Reprod Med Biol. 2022 May 23;21(1):e12467. doi: 10.1002/rmb2.12467. eCollection Jan-Dec 2022. https://pubmed.ncbi.nlm.nih.gov/35619658/
Noda T, Blaha A, Fujihara Y, Gert KR, Emori C, Deneke VE, Oura S, Panser K, Lu Y, Berent S, Kodani M, Cabrera-Quio LE, #Pauli A, #Ikawa M.
Sperm membrane proteins DCST1 and DCST2 are required for sperm-egg interaction in mice and fish. Commun Biol. 2022 Apr 7;5(1):332. doi: 10.1038/s42003-022-03289-w. https://pubmed.ncbi.nlm.nih.gov/35393517/
Hiramatsu Y, Suzuki K, Nishida T, Onoda N, Satoh T, Akira S, Ikawa M, Ikeda H, Kamei J, Derouiche S, Tominaga M, #Horiguchi Y.
The Mechanism of Pertussis Cough Revealed by the Mouse-Coughing Model. mBio.2022 Mar 31;e0319721. doi: 10.1128/mbio.03197-21. Online ahead of print. https://pubmed.ncbi.nlm.nih.gov/35357202/
El Hussien MA, Tsai CY, Satouh Y, Motooka D, Okuzaki D, Ikawa M, #Kikutani H, #Sakakibara S.
Corrigendum to: Multiple tolerance checkpoints restrain affinity maturation of B cells expressing the germline precursor of a lupus patient-derived anti-dsDNA antibody in knock-in mice. Int Immunol.2022 Mar 25;34(4):225. doi: 10.1093/intimm/dxac007. https://pubmed.ncbi.nlm.nih.gov/35348696/
Yamauchi Y, Matsumura T, Bakse J, Holmlund H, Blanchet G, Carrot E, Ikawa M, #Ward MA.
Loss of mouse Y chromosome gene Zfy1 and Zfy2 leads to spermatogenesis impairment, sperm defects, and infertility. Biol Reprod. 2022 Mar 16;ioac057. doi: 10.1093/biolre/ioac057. Online ahead of print. https://pubmed.ncbi.nlm.nih.gov/35293998/
Mise S, #Matsumoto A, Shimada K, Hosaka T, Takahashi M, Ichihara K, Shimizu H, Shiraishi C, Saito D, Suyama M, Yasuda T, Ide T, Izumi Y, Bamba T, Kimura-Someya T, Shirouzu M, Miyata H, Ikawa M, #Nakayama KI.
Kastor and Polluks polypeptides encoded by a single gene locus cooperatively regulate VDAC and spermatogenesis. Nat Commun. 2022 Feb 28;13(1):1071. doi: 10.1038/s41467-022-28677-y. https://pubmed.ncbi.nlm.nih.gov/35228556/
Hirata T, Kobayashi A, Furuse T, Yamada I, Tamura M, Tomita H, Tokoro Y, Ninomiya A, Fujihara Y, Ikawa M, Maeda Y, Murakami Y, #Kizuka Y, #Kinoshita T.
Loss of the N-acetylgalactosamine side chain of the GPI-anchor impairs bone formation and brain functions and accelerates the prion disease pathology. J Biol Chem. 2022 Feb 10;101720. doi: 10.1016/j.jbc.2022.101720. Online ahead of print. https://pubmed.ncbi.nlm.nih.gov/35151686/
#Miyata H, Oyama Y, Kaneda Y, #Ikawa M.
The motor domain of testis-enriched kinesin KIF9 is essential for its localization in the mouse flagellum. Exp Anim. 2022 Feb 9;71(1):46-52. doi: 10.1538/expanim.21-0082. Epub 2021 Sep 15. https://pubmed.ncbi.nlm.nih.gov/34526446/
Matsumura T, Noda T, Satouh Y, Morohoshi A, Yuri S, Ogawa M, Lu Y, Isotani A, #Ikawa M.
Sperm IZUMO1 Is Required for Binding Preceding Fusion With Oolemma in Mice and Rats. Front Cell Dev Biol. 2022 Jan 12;9:810118. doi: 10.3389/fcell.2021.810118. eCollection 2021. https://pubmed.ncbi.nlm.nih.gov/35096839/
Hwang JY, Wang H, Lu Y, Ikawa M, #Chung JJ.
C2cd6-encoded CatSperτ targets sperm calcium channel to Ca 2+ signaling domains in the flagellar membrane. Cell Rep. 2022 Jan 18;38(3):110226. doi: 10.1016/j.celrep.2021.110226. Epub 2022 Jan 7. https://pubmed.ncbi.nlm.nih.gov/34998468