FBXO24 deletion causes abnormal accumulation of membraneless electron-dense granules in sperm flagella and male infertility
KanedaY, #Miyata H, Xu Z , ShimadaK, Kamoshita M, Nakagawa T, Emori C, #Ikawa M Elife. 2024 Aug 20:13:RP92794. doi: 10.7554/eLife.92794. https://pubmed.ncbi.nlm.nih.gov/39163107/
Eighteen genes primarily expressed in the testis are not required for male fertility in mice
Yamamoto K, #Hiradate Y , #Ikawa M Biol Reprod. 2024 Aug 6:ioae119. doi: 10.1093/biolre/ioae119. Online ahead of print. https://pubmed.ncbi.nlm.nih.gov/39105275/
MYCBPAP is a central apparatus protein required for centrosome-nuclear envelope docking and sperm tail biogenesis in mice
*Wang H, *Kobayashi H, Shimada K, Oura S, Oyama Y, Kitakaze H, Noda T, Yabuta N, #Miyata H, #Ikawa M J Cell Sci. 2024 Aug 2:jcs.261962. doi: 10.1242/jcs.261962. Online ahead of print. https://pubmed.ncbi.nlm.nih.gov/39092789/
Golgi associated RAB2 interactor protein family contributes to murine male fertility to various extents by assuring correct morphogenesis of sperm heads
Wang H, Iida-Norita R, Mashiko D, Pham AH,#Miyata H , #Ikawa M PLoS Genet.2024 Jun 27;20(6):e1011337. doi: 10.1371/journal.pgen.1011337. Online ahead of print. https://pubmed.ncbi.nlm.nih.gov/38935810/
Gene-deficient mouse model established by CRISPR/Cas9 system reveals 15 reproductive organ-enriched genes dispensable for male fertility
Nguyen TTT, #Tokuhiro K, Shimada K, Wang H, Mashiko D, Tonai S, Kiyozumi D, #Ikawa M Front Cell Dev Biol. 2024 May 21:12:1411162. doi: 10.3389/fcell.2024.1411162. eCollection 2024. https://pubmed.ncbi.nlm.nih.gov/38835510/
Pham AH, Emori C, Ishikawa-Yamauchi Y, Tokuhiro K, Kamoshita M, Fujihara Y, #Ikawa M.
Thirteen Ovary-Enriched Genes Are Individually Not Essential for Female Fertility in Mice Cells. 2024 May 8;13(10):802. doi: 10.3390/cells13100802. https://pubmed.ncbi.nlm.nih.gov/38786026/
Suzuki A, #Yabuta N , Shimada K, Mashiko D, Tokuhiro K, Oyama Y, Miyata H, Garcia TX, Matzuk MM, #Ikawa M
Individual disruption of 12 testis-enriched genes via the CRISPR/Cas9 system does not affect the fertility of male mice J Reprod Immunol. 2024 Apr 29:163:104252. doi: 10.1016/j.jri.2024.104252. Online ahead of print. https://pubmed.ncbi.nlm.nih.gov/38697008/
#Metwally H, Elbrashy MM, Ozawa T, Okuyama K, White JT, Tulyeu J, Søndergaard JN, Wing JB, Muratsu A, Matsumoto H, Ikawa M, Kishi H, Taniuchi I, #Kishimoto T.
Threonine phosphorylation of STAT1 restricts interferon signaling and promotes innate inflammatory responses Proc Natl Acad Sci U S A. 2024 Apr 23;121(17):e2402226121. doi: 10.1073/pnas.2402226121. Epub 2024 Apr 15. https://pubmed.ncbi.nlm.nih.gov/38621137/
#Noda T, Shinohara H, Kobayashi S, Taira A , Oura S, Tahara D, Tokuyasu M, Araki K, #Ikawa M.
Multiple genes in the Pate5-13 genomic region contribute to ADAM3 processing Biol Reprod. 2024 Apr 11;110(4):750-760. doi: 10.1093/biolre/ioae008. https://pubmed.ncbi.nlm.nih.gov/38217862/
Liao Z, Tang S, Nozawa K, Shimada K, Ikawa M, #Monsivais D, #Matzuk M.
Affinity-tagged SMAD1 and SMAD5 mouse lines reveal transcriptional reprogramming mechanisms during early pregnancy Elife.2024 Mar 27:12:RP91434. doi: 10.7554/eLife.91434. https://pubmed.ncbi.nlm.nih.gov/38536963/
Nishio S, Emori C, Wiseman B, Fahrenkamp D, Dioguardi E, Zamora-Caballero S, Bokhove M, Han L, Stsiapanava A, Algarra B, Lu Y, Kodani M, Bainbridge R E, Komondor K M, Carlson A E, Landreh M, Sanctis D, Yasumasu S, Ikawa M, #Jovine L
ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat Cell. 2024 Mar 14;187(6):1440-1459.e24. doi: 10.1016/j.cell.2024.02.013. https://pubmed.ncbi.nlm.nih.gov/38490181/
Kent K , Nozawa K , Sutton C , Daniel F , Ikawa M , Garcia TX, #Matzuk MM
CUB domains are not required for OVCH2 function in sperm maturation in the mouse epididymis
Andrology. 2024 Mar;12(3):682-697. doi: 10.1111/andr.13508. Epub 2023 Aug 8.
#Fujihara Y, Miyata H, Abbasi F, Larasati T, Nozawa K, Yu Z, Ikawa M, Matzuk MM Tex46 knockout male mice are sterile secondary to sperm head malformations and failure to penetrate through the zona pellucida PNAS Nexus. 2024 Mar 12;3(3):pgae108. doi: 10.1093/pnasnexus/pgae108. eCollection 2024 Mar. https://pubmed.ncbi.nlm.nih.gov/38516277/
*Emori C, *Kodani M, Abbasi F, Mori M , #Ikawa M
PABPN1L is required for maternal mRNA degradation after meiosis resumption J Reprod Dev. 2024 Feb 19;70(1):10-17. doi: 10.1262/jrd.2023-077. Epub 2023 Dec 7. https://pubmed.ncbi.nlm.nih.gov/38057116/
#Endo T, Kobayashi K, Matsumura T, Emori C, Ozawa M, Kawamoto S, Okuzaki D, Shimada K, Miyata H, Shimada K, Kodani M, Ishikawa-Yamauchi Y, Motooka D, Hara E, #Ikawa M.
Multiple ageing effects on testicular/epididymal germ cells lead to decreased male fertility in mice Commun Biol. 2024 Jan 4;7(1):16. doi: 10.1038/s42003-023-05685-2. https://pubmed.ncbi.nlm.nih.gov/38177279/