原著論文 Original Articles

2018年

  1. Carvajal G, Brukman NG, Weigel Muñoz M, Battistone MA, Guazzone VA, Ikawa M, Haruhiko M, Lustig L, Breton S, *Cuasnicu PS.
    Impaired male fertility and abnormal epididymal epithelium differentiation in mice lacking CRISP1 and CRISP4.
    Sci Rep. 2018 Dec 3;8(1):17531.
    https://www.ncbi.nlm.nih.gov/pubmed/30510210 

  2. Kiyozumi D, Taniguchi Y, Nakano I, Toga J, Yagi E, Hasuwa H, Ikawa M, *Sekiguchi K.
    Laminin γ1 C-terminal Glu to Gln mutation induces early postimplantation lethality.
    Life Sci Alliance. 2018 Sep 10;1(5):e201800064.
    https://www.ncbi.nlm.nih.gov/pubmed/30456378
     
  3. Suzuki T, *Okamoto T, Katoh H, Sugiyama Y, Kusakabe S, Tokunaga M, Hirano J, Miyata Y, Fukuhara T, Ikawa M, Satoh T, Yoshio S, Suzuki R, Saijo M, Huang DCS, Kanto T, Akira S, *Matsuura Y.
    Infection with flaviviruses requires BCLXL for cell survival.
    PLoS Pathog. 2018 Sep 27;14(9):e1007299.
    https://www.ncbi.nlm.nih.gov/pubmed/30261081
     
  4. Sakamoto S, *Thumkeo D, Ohta H, Zhang Z, Huang S, Kanchanawong P, Fuu T, Watanabe S, Shimada K, Fujihara Y, Yoshida S, Ikawa M, Watanabe N, Saitou M, *Narumiya S.
    mDia1/3 generate cortical F-actin meshwork in Sertoli cells that is continuous with contractile F-actin bundles and indispensable for spermatogenesis and male fertility.
    PLoS Biol. 2018 Sep 26;16(9):e2004874.
    https://www.ncbi.nlm.nih.gov/pubmed/30256801 
     
  5. Fujihara Y, Oji A, Kojima-Kita K, Larasati T, *Ikawa M.
    Co-expression of sperm membrane proteins CMTM2A and CMTM2B is essential for ADAM3 localization and male fertility in mice.
    J Cell Sci.2018 Oct 8;131(19). pii: jcs221481.
    https://www.ncbi.nlm.nih.gov/pubmed/30209135
    Research Highlightとして紹介  
     
  6. Abbasi F, Miyata H, Shimada K, Morohoshi A, Nozawa K, Matsumura Y, Xu Z, Pratiwi P, *Ikawa M.
    RSPH6A is required for sperm flagellum formation and male fertility in mice.
    J Cell Sci. 2018 Oct 11;131(19).
    https://www.ncbi.nlm.nih.gov/pubmed/30185526
     
  7. *Nishimasu H, Shi X, Ishiguro S, Gao L, Hirano S, Okazaki S, Noda T, Abudayyeh OO, Gootenberg JS, Mori H, Oura S, Holmes B, Tanaka M, Seki M, Hirano H, Aburatani H, Ishitani R, Ikawa M, Yachie N, Zhang F, *Nureki O.
    Engineered CRISPR-Cas9 nuclease with expanded targeting space.
    Science. 2018 Aug 30. pii: eaas9129.
    https://www.ncbi.nlm.nih.gov/pubmed/30166441
     
  8. Aoki A, Nakashima A, Kusabiraki T, Ono Y, Yoshino O, Muto M, Kumasawa K, Yoshimori T, Ikawa M, Saito S.
    Trophoblast-Specific Conditional Atg7 Knockout Mice Develop Gestational Hypertension.
    Am J Pathol. 2018 Aug 27. pii: S0002-9440(18)30366-3.
    https://www.ncbi.nlm.nih.gov/pubmed/30165042
     
  9. *Fustin JM, Kojima R, Itoh K, Chang HY, Ye S, Zhuang B, Oji A, Gibo S, Narasimamurthy R, Virshup D, Kurosawa G, Doi M, Manabe I, Ishihama Y, Ikawa M, *Okamura H.
    Two Ck1δ transcripts regulated by m6A methylation code for two antagonistic kinases in the control of the circadian clock.
    Proc Natl Acad Sci U S A. Jun 5;115(23):5980-5985.
    https://www.ncbi.nlm.nih.gov/pubmed/29784786
     
  10. *Tanaka T, Shimizu S, Ueno M, Fujihara Y, Ikawa M, Miyata S.
    MARCKSL1 Regulates Spine Formation in the Amygdala and Controls the Hypothalamic-Pituitary-Adrenal Axis and Anxiety-Like Behaviors.
    EBioMedicine. Apr;30:62-73.
    https://www.ncbi.nlm.nih.gov/pubmed/29580842
     
  11. Murase M, *Kawasaki T, Hakozaki R, Sueyoshi T, Putri DDP, Kitai Y, Sato S, Ikawa M, *Kawai T.
    Intravesicular Acidification Regulates Lipopolysaccharide Inflammation and Tolerance through TLR4 Trafficking.
    J Immunol. Apr 15;200(8):2798-2808.
    https://www.ncbi.nlm.nih.gov/pubmed/29540576
     
  12. Shibata T, Shibata S, Ishigaki Y, Kiyokawa E, Ikawa M, Singh DP, Sasaki H, *Kubo E.
    Tropomyosin 2 heterozygous knockout in mice using CRISPR-Cas9 system displays the inhibition of injury-induced epithelial-mesenchymal transition, and lens opacity.
    Mech Ageing Dev. Apr;171:24-30.
    https://www.ncbi.nlm.nih.gov/pubmed/29510160
     
  13. Fujita T, Kitaura F, Oji A, Tanigawa N, Yuno M, Ikawa M, Taniuchi I, *Fujii H.
    Transgenic mouse lines expressing the 3xFLAG-dCas9 protein for enChIP analysis.
    Genes Cells. Apr;23(4):318-325.
    https://www.ncbi.nlm.nih.gov/pubmed/29480524
     
  14. Nozawa K, Satouh Y, Fujimoto T, Oji A, *Ikawa M.
    Sperm-borne phospholipase C zeta-1 ensures monospermic fertilization in mice.
    Sci Rep. Jan 22;8:1315.
    https://www.ncbi.nlm.nih.gov/pubmed/29358633