原著論文 Original Articles

2022年

*equal contribution #corresponding author

  1. Nozawa K, Fujihara Y, Devlin DJ, Deras RE, Kent K, Larina IV, Umezu K, Yu Z, Sutton CM, Ye Q, Dean LK, Emori C, Ikawa M, Garcia TX, #Matzuk MM.
    The testis-specific E3 ubiquitin ligase RNF133 is required for fecundity in mice.
    BMC Biol. 2022 Jul 13;20(1):161. doi: 10.1186/s12915-022-01368-2.
    https://pubmed.ncbi.nlm.nih.gov/35831855/
     
  2. Oura S, Hino T, Satoh T, Noda T, Koyano T, Isotani A, Matsuyama M, Akira S, Ishiguro KI, #Ikawa M.
    Trim41 is required to regulate chromosome axis protein dynamics and meiosis in male mice.
    PLoS Genet. 2022 Jun 1;18(6):e1010241. doi: 10.1371/journal.pgen.1010241. Online ahead of print.
    https://pubmed.ncbi.nlm.nih.gov/35648791/
     
  3. Kaneda Y, #Miyata H, Shimada K, Oyama Y, Iida-Norita R, #Ikawa M.
    IRGC1, a testis-enriched immunity related GTPase, is important for fibrous sheath integrity and sperm motility in mice.
    Dev Biol. 2022 May 23:S0012-1606(22)00099-9. doi: 10.1016/j.ydbio.2022.05.011. Online ahead of print.
    https://pubmed.ncbi.nlm.nih.gov/35618043/
     
  4. Oyama Y, #Miyata H, Shimada K, Larasati T, Fujihara Y, #Ikawa M
    TULP2 deletion mice exhibit abnormal outer dense fiber structure and male infertility.
    Reprod Med Biol. 2022 May 23;21(1):e12467. doi: 10.1002/rmb2.12467. eCollection Jan-Dec 2022.
    https://pubmed.ncbi.nlm.nih.gov/35619658/
     
  5. Noda T, Blaha A, Fujihara Y, Gert KR, Emori C, Deneke VE, Oura S, Panser K, Lu Y, Berent S, Kodani M, Cabrera-Quio LE, #Pauli A, #Ikawa M.
    Sperm membrane proteins DCST1 and DCST2 are required for sperm-egg interaction in mice and fish.
    Commun Biol. 2022 Apr 7;5(1):332. doi: 10.1038/s42003-022-03289-w.
    https://pubmed.ncbi.nlm.nih.gov/35393517/
     
  6. Hiramatsu Y, Suzuki K, Nishida T, Onoda N, Satoh T, Akira S, Ikawa M, Ikeda H, Kamei J, Derouiche S, Tominaga M, #Horiguchi Y.
    The Mechanism of Pertussis Cough Revealed by the Mouse-Coughing Model.
    mBio. 2022 Mar 31;e0319721. doi: 10.1128/mbio.03197-21. Online ahead of print.
    https://pubmed.ncbi.nlm.nih.gov/35357202/
     
  7. El Hussien MA, Tsai CY, Satouh Y, Motooka D, Okuzaki D, Ikawa M, #Kikutani H, #Sakakibara S.
    Corrigendum to: Multiple tolerance checkpoints restrain affinity maturation of B cells expressing the germline precursor of a lupus patient-derived anti-dsDNA antibody in knock-in mice.
    Int Immunol. 2022 Mar 25;34(4):225. doi: 10.1093/intimm/dxac007.
    https://pubmed.ncbi.nlm.nih.gov/35348696/
     
  8. Yamauchi Y, Matsumura T, Bakse J, Holmlund H, Blanchet G, Carrot E, Ikawa M, #Ward MA.
    Loss of mouse Y chromosome gene Zfy1 and Zfy2 leads to spermatogenesis impairment, sperm defects, and infertility.
    Biol Reprod. 2022 Mar 16;ioac057. doi: 10.1093/biolre/ioac057. Online ahead of print.
    https://pubmed.ncbi.nlm.nih.gov/35293998/
     
  9. Mise S, #Matsumoto A, Shimada K, Hosaka T, Takahashi M, Ichihara K, Shimizu H, Shiraishi C, Saito D, Suyama M, Yasuda T, Ide T, Izumi Y, Bamba T, Kimura-Someya T, Shirouzu M, Miyata H, Ikawa M, #Nakayama KI.
    Kastor and Polluks polypeptides encoded by a single gene locus cooperatively regulate VDAC and spermatogenesis.
    Nat Commun. 2022 Feb 28;13(1):1071. doi: 10.1038/s41467-022-28677-y.
    https://pubmed.ncbi.nlm.nih.gov/35228556/
     
  10. Hirata T, Kobayashi A, Furuse T, Yamada I, Tamura M, Tomita H, Tokoro Y, Ninomiya A, Fujihara Y, Ikawa M, Maeda Y, Murakami Y, #Kizuka Y, #Kinoshita T.
    Loss of the N-acetylgalactosamine side chain of the GPI-anchor impairs bone formation and brain functions and accelerates the prion disease pathology.
    J Biol Chem. 2022 Feb 10;101720. doi: 10.1016/j.jbc.2022.101720. Online ahead of print.
    https://pubmed.ncbi.nlm.nih.gov/35151686/
     
  11. #Miyata H, Oyama Y, Kaneda Y, #Ikawa M.
    The motor domain of testis-enriched kinesin KIF9 is essential for its localization in the mouse flagellum.
    Exp Anim. 2022 Feb 9;71(1):46-52. doi: 10.1538/expanim.21-0082. Epub 2021 Sep 15.
    https://pubmed.ncbi.nlm.nih.gov/34526446/
     
  12. Matsumura T, Noda T, Satouh Y, Morohoshi A, Yuri S, Ogawa M, Lu Y, Isotani A, #Ikawa M.
    Sperm IZUMO1 Is Required for Binding Preceding Fusion With Oolemma in Mice and Rats.
    Front Cell Dev Biol. 2022 Jan 12;9:810118. doi: 10.3389/fcell.2021.810118. eCollection 2021.
    https://pubmed.ncbi.nlm.nih.gov/35096839/
     
  13. Hwang JY, Wang H, Lu Y, Ikawa M, #Chung JJ.
    C2cd6-encoded CatSperτ targets sperm calcium channel to Ca 2+ signaling domains in the flagellar membrane.
    Cell Rep. 2022 Jan 18;38(3):110226. doi: 10.1016/j.celrep.2021.110226. Epub 2022 Jan 7.
    https://pubmed.ncbi.nlm.nih.gov/34998468