原著論文 Original Articles

2011年

  1. Inoue N, Satouh Y, Ikawa M, *Okabe M, *Yanagimachi R.
    Acrosome-reacted mouse spermatozoa recovered from the perivitelline space can fertilize other eggs.
    Proc Natl Acad Sci U S A. 2011 Dec 13;108(50):20008-11.
    http://www.ncbi.nlm.nih.gov/pubmed/22084105  
     
  2. Hayashi T, Nozaki Y, Nishizuka M, Ikawa M, Osada S, *Imagawa M.
    Factor for adipocyte differentiation 158 gene disruption prevents the body weight gain and insulin resistance induced by a high-fat diet.
    Biol Pharm Bull. 2011;34(8):1257-63.
    http://www.ncbi.nlm.nih.gov/pubmed/21804215  
     
  3. *Mitsutake S, Zama K, Yokota H, Yoshida T, Tanaka M, Mitsui M, Ikawa M, Okabe M, Tanaka Y, Yamashita T, Takemoto H, Okazaki T, Watanabe K, Igarashi Y.
    Dynamic modification of sphingomyelin in lipid microdomains controls development of obesity, fatty liver, and type 2 diabetes.
    J Biol Chem. 2011; 286(32):28544-55.
    http://www.ncbi.nlm.nih.gov/pubmed/21669879  
     
  4. *Kanatsu-Shinohara M, Kato-Itoh M, Ikawa M, Takehashi M, Sanbo M, Morioka Y, Tanaka T, Morimoto H, Hirabayashi M, Shinohara T.
    Homologous recombination in rat germline stem cells.
    Biol Reprod. 2011 Jul;85(1):208-17.
    http://www.ncbi.nlm.nih.gov/pubmed/21471297  
     
  5. Suga T, *Kimura E, Morioka Y, Ikawa M, Li S, Uchino K, Uchida Y, Yamashita S, Maeda Y, Chamberlain JS, Uchino M.
    Muscle fiber type-predominant promoter activity in lentiviral-mediated transgenic mouse.
    PLoS One. 2011 Mar 18;6(3):e16908.
    http://www.ncbi.nlm.nih.gov/pubmed/21445245  
     
  6. Nagai M, Moriyama T, Mehmood R, Tokuhiro K, Ikawa M, Okabe M, Tanaka H, *Yoneda Y.
    Mice lacking Ran binding protein 1 are viable and show male infertility.
    FEBS Lett. 2011; 585(5):791-6.
    http://www.ncbi.nlm.nih.gov/pubmed/21310149  
     
  7. Moriyama T, Nagai M, Oka M, Ikawa M, Okabe M, *Yoneda Y.
    Targeted disruption of one of the importin α family members leads to female functional incompetence in delivery.
    FEBS J. 2011; 278(9):1561-72.
    http://www.ncbi.nlm.nih.gov/pubmed/21371262  
     
  8. Isotani A, Hatayama H, Kaseda K, Ikawa M, *Okabe M.
    Formation of a thymus from rat ES cells in xenogeneic nude mouse?rat ES chimeras.
    Genes Cells. 2011; 16:397-405.
    http://www.ncbi.nlm.nih.gov/pubmed/21401810  
     
  9. Nakagawa Y, Takamatsu H, Okuno T, Kang S, Nojima S, Kimura T, Kataoka TR, Ikawa M, Toyofuku T, Katayama I, *Kumanogoh A.
    Identification of semaphorin 4B as a negative regulator of basophil-mediated immune responses.
    J Immunol. 2011 Mar 1;186(5):2881-8.
    http://www.ncbi.nlm.nih.gov/pubmed/21270411  
     
  10. *Yano M, Watanabe K, Yamamoto T, Ikeda K, Senokuchi T, Lu M, Kadomatsu T, Tsukano H, Ikawa M, Okabe M, Yamaoka S, Okazaki T, Umehara H, Gotoh T, Song WJ, Node K, Taguchi R, Yamagata K, *Oike Y.
    Mitochondrial dysfunction and increased reactive oxygen species impair insulin secretion in sphingomyelin synthase 1-null mice.
    J Biol Chem. 2011; 286(5):3992-4002.
    http://www.ncbi.nlm.nih.gov/pubmed/21115496  
     
  11. Kumasawa K, *Ikawa M, Kidoya H, Hasuwa H, Saito-Fujita T, Morioka Y, Takakura N, Kimura T, Okabe M.
    Pravastatin induces placental growth factor (PGF) and ameliorates preeclampsia in a mouse model.
    Proc Natl Acad Sci U S A 2011; 108:1451-1455.
    http://www.ncbi.nlm.nih.gov/pubmed/21187414
    微生物病研究所 「主な研究成果」 紹介ページへ  
     
  12. *Ikawa M, Tokuhiro K, Yamaguchi R, Benham AM, Tamura T, Wada I, Satouh Y, Inoue N, Okabe M.
    Calsperin is a testis-specific chaperone required for sperm fertility.
    J Biol Chem. 2011; 286(7):5639-46.
    http://www.ncbi.nlm.nih.gov/pubmed/21131354