原著論文 Original Articles

2013年

  1. Mashiko D, Fujihara Y, Satouh Y, Miyata H, Isotani A, *Ikawa M.
    Generation of mutant mice by pronuclear injection of circular plasmid expressing Cas9 and single guided RNA.
    Sci Rep. 2013 Nov 27;3:3355.
    http://www.ncbi.nlm.nih.gov/pubmed/24284873  
     
  2. Ochiai N, Nishizuka M, Miyamoto T, Miyoshi I, Ikawa M, Osada S, *Imagawa M.
    Targeted disruption of fad24, a regulator of adipogenesis, causes pre-implantation embryonic lethality due to the growth defect at the blastocyst stage.
    Biochem Biophys Res Commun. 2013 Aug 23;438(2):301-5.
    http://www.ncbi.nlm.nih.gov/pubmed/23886952  
     
  3. Suzuki N, Kunishima S, Ikejiri M, Maruyama S, Sone M, Takagi A, Ikawa M, Okabe M, Kojima T, Saito H, Naoe T, *Matsushita T.
    Establishment of mouse model of MYH9 disorders: heterozygous R702C mutation provokes macrothrombocytopenia with leukocyte inclusion bodies, renal glomerulosclerosis and hearing disability.
    PLoS One. 2013 Aug 20;8(8):e71187.
    http://www.ncbi.nlm.nih.gov/pubmed/23976996  
     
  4. Tashiro-Yamaji J, Maeda S, Ikawa M, Okabe M, Kubota T, *Yoshida R.
    Macrophage MHC and T-cell receptors essential for rejection of allografted skin and lymphoma.
    Transplantation. 2013 Aug 15;96(3):251-7.
    http://www.ncbi.nlm.nih.gov/pubmed/23836286  
     
  5. Inoue N, Hamada D, Kamikubo H, Hirata K, Kataoka M, Yamamoto M, Ikawa M, Okabe M and *Hagihara Y.
    Molecular dissection of IZUMO1, a sperm protein essential for sperm-egg fusion.
    Development. 2013 Aug;140(15):3221-9.
    http://www.ncbi.nlm.nih.gov/pubmed/23824580  
     
  6. Hasuwa H, Ueda J, Ikawa M, *Okabe M.
    MiR-200b and miR-429 Function in Mouse Ovulation and Are Essential for Female Fertility.
    Science. 2013 Jul 5;341(6141):71-3.
    http://www.ncbi.nlm.nih.gov/pubmed/23765281
    PDF file
    微生物病研究所 「主な研究成果」 紹介ページへ  
     
  7. Naito Y, Yabuta N, Sato J, Ohno S, Sakata M, Kasama T, Ikawa M, *Nojima H.
    Recruitment of cyclin G2 to promyelocytic leukemia nuclear bodies promotes dephosphorylation of γH2AX following treatment with ionizing radiation.
    Cell Cycle. 2013 Jun 1;12(11):1773-84.
    http://www.ncbi.nlm.nih.gov/pubmed/23656780  
     
  8. Fujihara Y, Tokuhiro K, Muro Y, Kondoh G, Araki Y, Ikawa M, *Okabe M.
    Expression of TEX101, regulated by ACE, is essential for the production of fertile mouse spermatozoa.
    Proc Natl Acad Sci U S A. 2013 May 14;110(20):8111-6.
    http://www.ncbi.nlm.nih.gov/pubmed/23633567  
     
  9. Nojima S, *Toyofuku T, Kamao H, Ishigami C, Kaneko J, Okuno T, Takamatsu H, Ito D, Kang S, Kimura T, Yoshida Y, Morimoto K, Maeda Y, Ogata A, Ikawa M, Morii E, Aozasa K, Takagi J, Takahashi M, *Kumanogoh A.
    A point mutation in Semaphorin 4A associates with defective endosomal sorting and causes retinal degeneration.
    Nat Commun. 2013;4:1406.
    http://www.ncbi.nlm.nih.gov/pubmed/23360997  
     
  10. Fujihara Y, Kaseda K, Inoue N, Ikawa M, *Okabe M.
    Production of mouse pups from germline transmission-failed knockout chimeras.
    Transgenic Res. 2013 Feb;22(1):195-200.
    http://www.ncbi.nlm.nih.gov/pubmed/22826106  
     
  11. Yabuta N, Mukai S, Okamoto A, Okuzaki D, Suzuki H, Torigata K, Yoshida K, Okada N, Miura D, Ito A, Ikawa M, Okabe M, *Nojima H.
    N-terminal truncation of Lats1 causes abnormal cell growth control and chromosomal instability.
    J Cell Sci. 2013 Jan 15;126(Pt 2):508-20.
    http://www.ncbi.nlm.nih.gov/pubmed/23230145  
     
  12. Wang J, Shiratori I, Uehori J, Ikawa M, *Arase H.
    Neutrophil infiltration during inflammation is regulated by PILRα via modulation of integrin activation.
    Nat Immunol. 2013 Jan;14(1):34-40.
    http://www.ncbi.nlm.nih.gov/pubmed/23142774